Preparation of Xenon-133 Solution for Intravenous Administration

نویسنده

  • Mrinal K. Dewanjee
چکیده

A method for routine preparation of a solution of 133 Xe gas in saline from commercially available m Xe gas ampoules is described and evaluated. At room temperature and atmospheric pressure, about 25% of the mxe gas dissolves in saline. Xenon-133 binds to the syringe wall or may escape into the air when stored in sealed plastic syringes. Preparation immediately prior to use, short-term storage in a properly closed glass vial, and assay of the syringe for activity before and after injection are important considerations for delivering accurate amounts of mxe gas in saline solution.

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تاریخ انتشار 2014